Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583673 | 0.97 | EGFR (0.48) | EGFRKDR | |
| SCHEMBL4582514 | 0.94 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL4583945 | 0.90 | EGFR (0.46) | EGFRKDR | |
| SCHEMBL4584112 | 0.87 | MAPT (0.44) | — | |
| SCHEMBL4583133 | 0.87 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL4584003 | 0.86 | MEN1 (0.51) | — | |
| SCHEMBL4582536 | 0.85 | KMT2A (0.48) | EGFRKDR | |
| SCHEMBL4584224 | 0.84 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL4779982 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL4582338 | 0.83 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |