Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582950 | 0.94 | ALDH1A1 (0.52) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4583177 | 0.93 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4726941 | 0.92 | PDGFRB (0.49) | PDGFRB | |
| SCHEMBL4582928 | 0.88 | PKM (0.52) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4583521 | 0.88 | PDGFRB (0.55) | ALDH1A1LMNAPDGFRB | |
| SCHEMBL4583138 | 0.86 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4583908 | 0.86 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4582318 | 0.85 | MEN1 (0.56) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4583992 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNAPDGFRB | |
| SCHEMBL4582248 | 0.85 | PDGFRB (0.45) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |