Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930330 | 0.83 | PNMT (0.50) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL11084369 | 0.83 | PNMT (0.50) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL625631 | 0.81 | PNMT (0.47) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL4726331 | 0.81 | PNMT (0.47) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL29072738 | 0.81 | PNMT (0.51) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL22930915 | 0.81 | PNMT (0.47) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL20963104 | 0.78 | PNMT (0.45) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL12251272 | 0.78 | PNMT (0.45) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL15391010 | 0.78 | PNMT (0.47) | PNMTIDO1TDO2ACP3CES2 | |
| SCHEMBL19592385 | 0.77 | PNMT (0.44) | PNMTIDO1TDO2ACP3CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |