Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733316 | 0.92 | CCR2 (0.31) | CCR2 | |
| SCHEMBL4729719 | 0.84 | CCR2 (0.37) | CCR2 | |
| SCHEMBL4732208 | 0.80 | CCR2 (0.36) | CCR2 | |
| SCHEMBL4728688 | 0.79 | CCR2 (0.36) | CCR2 | |
| SCHEMBL4004874 | 0.76 | — | — | |
| SCHEMBL4728127 | 0.74 | CCR2 (0.36) | CCR2 | |
| SCHEMBL4730586 | 0.74 | TACR1 (0.34) | — | |
| SCHEMBL3998807 | 0.73 | SMYD3 (0.31) | — | |
| SCHEMBL4731403 | 0.73 | TACR1 (0.33) | CCR2 | |
| SCHEMBL4732499 | 0.72 | TACR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |