Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728199 | 0.86 | MMP13 (0.45) | KMT2ASMN1; SMN2ALDH1A1MEN1USP2 | |
| SCHEMBL4731617 | 0.81 | PKM (0.41) | — | |
| SCHEMBL9693010 | 0.77 | GGPS1 (0.55) | GGPS1KMT2ASLC13A5CYP2D6ROCK2 | |
| SCHEMBL12866793 | 0.74 | GGPS1 (0.50) | GGPS1KMT2ACYP2D6ROCK2CYP3A4 | |
| SCHEMBL11209969 | 0.71 | PLA2G4B (0.61) | GGPS1CYP2D6PLA2G4B | |
| SCHEMBL10235871 | 0.71 | SLC13A5 (0.49) | GGPS1KMT2ASLC13A5CYP2D6CA1 | |
| SCHEMBL4730808 | 0.71 | SLC13A5 (0.39) | KMT2ASLC13A5MAPTL3MBTL1TDP1 | |
| SCHEMBL4901983 | 0.71 | KMT2A (0.43) | GGPS1KMT2ACYP2D6ROCK2CYP3A4 | |
| SCHEMBL10455393 | 0.70 | PLA2G4B (0.67) | KMT2AMEP1BL3MBTL1FAAHPLA2G4B | |
| SCHEMBL15568242 | 0.70 | KMT2A (0.53) | GGPS1KMT2ACYP2D6ROCK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036308-A2 | AMINO-SUBSTITUTED HETEROCYCLES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-03-27 | — | — | WO | disclosed |