Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 11/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726728 | 0.92 | NPY5R (0.58) | HDAC6HDAC1HDAC10MAPTMEN1 | |
| SCHEMBL7722872 | 0.87 | MAPT (0.75) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4729244 | 0.85 | NPSR1 (0.76) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL1149521 | 0.85 | MAPT (0.59) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4730104 | 0.84 | NPY5R (0.67) | HDAC6MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL1149959 | 0.83 | MAPT (0.57) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4727925 | 0.82 | NPY5R (0.65) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4728967 | 0.82 | KDM4E (0.64) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4728971 | 0.82 | KDM4E (0.64) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4725134 | 0.82 | MAPT (0.77) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |