Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729164 | 0.94 | TACR1 (0.35) | TACR1TSHRCCR2SLC6A4 | |
| SCHEMBL4733058 | 0.89 | TRPV1 (0.36) | TACR1 | |
| SCHEMBL4730021 | 0.87 | TACR1 (0.38) | TACR1SLC6A4 | |
| SCHEMBL4732027 | 0.86 | TACR1 (0.38) | TACR1SLC6A4 | |
| SCHEMBL4730613 | 0.85 | TACR1 (0.35) | TACR1SLC6A4 | |
| SCHEMBL4730989 | 0.85 | CETP (0.38) | TACR1CCR2 | |
| SCHEMBL4731394 | 0.84 | TRPV1 (0.42) | — | |
| SCHEMBL4728683 | 0.84 | KDM4E (0.40) | TACR1 | |
| SCHEMBL4733037 | 0.83 | KCNH2 (0.41) | TACR1CCR2SLC6A4 | |
| SCHEMBL4731956 | 0.82 | TACR1 (0.46) | TACR1CCR2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |