Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 16/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728683 | 0.93 | KDM4E (0.40) | CETPTACR1 | |
| SCHEMBL4730021 | 0.89 | TACR1 (0.38) | TACR1 | |
| SCHEMBL4728797 | 0.88 | CCR2 (0.38) | CETPTACR1CCR2 | |
| SCHEMBL4732027 | 0.87 | TACR1 (0.38) | TACR1 | |
| SCHEMBL4729901 | 0.86 | CETP (0.38) | CETPTACR1CCR2 | |
| SCHEMBL4730613 | 0.85 | TACR1 (0.35) | TACR1 | |
| SCHEMBL4730403 | 0.85 | TACR1 (0.35) | TACR1CCR2 | |
| SCHEMBL4729068 | 0.84 | TACR1 (0.36) | CETPTACR1 | |
| SCHEMBL4733037 | 0.84 | KCNH2 (0.41) | TACR1CCR2 | |
| SCHEMBL4733058 | 0.84 | TRPV1 (0.36) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |