⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19581184 | 0.92 | ALDH1A1 (0.45) | — | |
| SCHEMBL19581188 | 0.92 | ALDH1A1 (0.45) | — | |
| SCHEMBL5556899 | 0.83 | MEN1 (0.47) | — | |
| SCHEMBL13763536 | 0.81 | NPC1 (0.59) | — | |
| SCHEMBL27469120 | 0.78 | NPC1 (0.53) | — | |
| SCHEMBL1466424 | 0.77 | — | — | |
| SCHEMBL30203797 | 0.77 | — | — | |
| SCHEMBL1345285 | 0.77 | — | — | |
| SCHEMBL28322436 | 0.77 | — | — | |
| SCHEMBL80955 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | claimed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | claimed |
| EP-0184287-A1 | Pyridylaminoethenes | MAY & BAKER LIMITED (GB) | 1986-06-11 | — | — | EP | claimed |
| US-20170327944-A1 | ALUMINUM PRECURSORS FOR THIN-FILM DEPOSITION, PREPARATION METHOD AND USE THEREOF | Institute of Microelectronics, Chinese Academy of Sciences (CN) | 2017-11-16 | — | — | US | disclosed |
| EP-3088400-A1 | PYRROLO[2,3-B]PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON INC. (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |
| EP-0586556-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE HERBICIDES | ROHM & HAAS (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0586556-A1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE HERBICIDES. | MONSANTO CO (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5169432-A | 2-and/or 6-fluoroalkyl substituted and a carbonyl oxy(thio) ester or a heterocyclo-carbonyl at the 3 or 5 position | MONSANTO COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| WO-1992020659-A1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE HERBICIDES | MONSANTO COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0184287-A1 | Pyridylaminoethenes | MAY & BAKER LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
| EP-0184287-A1 | Pyridylaminoethenes | MAY & BAKER LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
| EP-0184287-A1 | Pyridylaminoethenes | MAY & BAKER LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |