Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832189 | 1.00 | CA2 (0.47) | CA2CA4MMEGAAMAPT | |
| SCHEMBL5611391 | 1.00 | CA2 (0.47) | CA2CA4MMEGAAMAPT | |
| SCHEMBL6620753 | 0.84 | ITGB2 (0.47) | CA2CA1TMPRSS15FOLH1 | |
| SCHEMBL19463542 | 0.84 | ITGB2 (0.47) | CA2CA1TMPRSS15FOLH1 | |
| SCHEMBL6620751 | 0.84 | ITGB2 (0.47) | CA2CA1TMPRSS15FOLH1 | |
| SCHEMBL7772671 | 0.82 | ECE1 (0.43) | CA2CA4FOLH1RIMKLANAALAD2 | |
| SCHEMBL4216202 | 0.82 | CA2 (0.33) | CA2CA4TMPRSS15 | |
| SCHEMBL5350166 | 0.82 | SLC22A6 (0.33) | CA2CA4GAAMAPTSLC22A6 | |
| SCHEMBL5344417 | 0.82 | SLC22A6 (0.33) | CA2CA4GAAMAPTSLC22A6 | |
| SCHEMBL7834369 | 0.82 | SLC22A6 (0.33) | CA2CA4GAAMAPTSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099793-B1 | AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK CANADA INC (CA) | 2012-02-01 | — | — | EP | disclosed |
| EP-0334236-B1 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5302743-A | Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0334236-A2 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-27 | — | — | EP | disclosed |
| US-4338346-A | Non-nutritive sweetener | THE PROCTER & GAMBLE COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0013044-A1 | L-aspartyl amide derivatives and their use as sweetening agents | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |