Biphenyl

Biphenyl

SCHEMBL4730719

C1CCC(C2CCCCC2)CC1.C=C.N.N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
SLC18A3 Q16572 1/20 0.35
HSD17B10 Q99714 1/20 0.33
HSD11B1 P28845 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL9853201 0.96 ALDH1A1 (0.73) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Biphenyl SCHEMBL1579788 0.91 ALDH1A1 (0.80) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Biphenyl SCHEMBL19245 0.91 ALDH1A1 (0.80) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Ethylene SCHEMBL11509833 0.91 ALDH1A1 (0.80) ALDH1A1SLC18A3
Ammonia Solution, Strong SCHEMBL16004680 0.91 ALDH1A1 (0.80) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Ammonia Solution, Strong SCHEMBL27750005 0.91 ALDH1A1 (0.80) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Ammonia Solution, Strong SCHEMBL27529417 0.91 ALDH1A1 (0.80) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Biphenyl SCHEMBL3924499 0.87 ALDH1A1 (0.73) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Biphenyl SCHEMBL8628717 0.87 ALDH1A1 (0.73) ALDH1A1SLC18A3HSD17B10HSD11B1CES2
Biphenyl SCHEMBL7916980 0.87 ALDH1A1 (0.73) ALDH1A1SLC18A3HSD17B10HSD11B1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008046557-A1 DENTAL OBTURATOR POINT DENTSPLY DE TREY GMBH (DE) 2008-04-24 WO claimed
EP-1416901-A1 DENTAL ROOT CANAL FILLING CONES DENTSPLY INTERNATIONAL, INC. (US) 2004-05-12 EP claimed
WO-2003015718-A1 DENTAL ROOT CANAL FILLING CONES DENTSPLY INTERNATIONAL INC. (US) 2003-02-27 WO claimed
WO-2008046557-A1 DENTAL OBTURATOR POINT DENTSPLY DE TREY GMBH (DE) 2008-04-24 WO disclosed
EP-1416901-A1 DENTAL ROOT CANAL FILLING CONES DENTSPLY INTERNATIONAL, INC. (US) 2004-05-12 EP disclosed
WO-2003015718-A1 DENTAL ROOT CANAL FILLING CONES DENTSPLY INTERNATIONAL INC. (US) 2003-02-27 WO disclosed