Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729719 | 0.75 | CCR2 (0.37) | TACR1SLC6A4CYP3A4CYP2D6CCR2 | |
| SCHEMBL4728127 | 0.74 | CCR2 (0.36) | TACR1SLC6A4CCR2 | |
| SCHEMBL4732208 | 0.74 | CCR2 (0.36) | TACR1SLC6A4CYP3A4CYP2D6CCR2 | |
| SCHEMBL4730370 | 0.72 | TACR1 (0.35) | TACR1SLC6A4CCR2TSHR | |
| SCHEMBL4728919 | 0.72 | TACR1 (0.36) | TACR1SLC6A4 | |
| SCHEMBL4729901 | 0.72 | CETP (0.38) | TACR1CCR2 | |
| SCHEMBL3023605 | 0.71 | CCR2 (0.44) | CCR2 | |
| SCHEMBL4003938 | 0.71 | KCNH2 (0.35) | TACR1SLC6A4TSHR | |
| SCHEMBL4001725 | 0.71 | TACR1 (0.39) | TACR1SLC6A4CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL4729389 | 0.71 | CCR2 (0.36) | TACR1SLC6A4CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |