Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733846 | 0.83 | UTS2R (0.40) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL4733624 | 0.83 | VDR (0.42) | ALDH1A1KMT2AVDRMEN1GAA | |
| SCHEMBL4731501 | 0.83 | CHRM2 (0.44) | MAPTTP53ALDH1A1TDP1 | |
| SCHEMBL4728454 | 0.80 | ACP3 (0.36) | PGR | |
| SCHEMBL4728806 | 0.79 | HTT (0.43) | ALDH1A1ALOX12TDP1KMT2AVDR | |
| SCHEMBL4734492 | 0.76 | VDR (0.38) | MAPTTP53ALDH1A1KMT2AVDR | |
| SCHEMBL768346 | 0.75 | ADRB3 (0.46) | MAPTTP53THRBPGRALDH1A1 | |
| SCHEMBL2536163 | 0.75 | ADRB3 (0.46) | MAPTTP53THRBPGRALDH1A1 | |
| SCHEMBL767895 | 0.75 | ADRB3 (0.46) | MAPTTP53THRBPGRALDH1A1 | |
| SCHEMBL4731994 | 0.75 | ACHE (0.39) | TP53THRBALDH1A1KMT2AVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054155-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |