Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.45 |
| ▸ | CCR2 | P41597 | 8/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732647 | 0.86 | CCR2 (0.43) | TACR1CCR2 | |
| SCHEMBL4782017 | 0.85 | CCR2 (0.41) | TACR1CCR2 | |
| SCHEMBL4780749 | 0.83 | CCR2 (0.46) | TACR1CCR2 | |
| SCHEMBL4731707 | 0.74 | TACR1 (0.41) | TACR1CCR2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3042043 | 0.69 | CCR2 (0.49) | TACR1CCR2 | |
| SCHEMBL4731860 | 0.68 | CCR2 (0.49) | TACR1CCR2 | |
| SCHEMBL14169574 | 0.68 | CCR2 (0.66) | CCR2 | |
| SCHEMBL14169710 | 0.67 | CCR2 (0.50) | TACR1CCR2 | |
| SCHEMBL7919878 | 0.67 | EPHX1 (0.50) | SMYD3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4727699 | 0.66 | CETP (0.39) | TACR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |