Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732647 | 0.88 | CCR2 (0.43) | CCR2TACR1 | |
| SCHEMBL4780749 | 0.86 | CCR2 (0.46) | CCR2TACR1 | |
| SCHEMBL4731708 | 0.85 | TACR1 (0.45) | CCR2TACR1 | |
| SCHEMBL4782016 | 0.74 | CCR2 (0.38) | CCR2TACR1CYP2D6TSHR | |
| SCHEMBL4727704 | 0.70 | CCR2 (0.51) | CCR2TACR1 | |
| SCHEMBL3023614 | 0.69 | CCR2 (0.51) | CCR2CYP2D6TSHR | |
| SCHEMBL4732759 | 0.65 | CCR2 (0.49) | CCR2 | |
| SCHEMBL4727699 | 0.65 | CETP (0.39) | CCR2TACR1 | |
| SCHEMBL4731341 | 0.65 | CCR2 (0.56) | CCR2 | |
| SCHEMBL4731356 | 0.65 | TACR1 (0.44) | CCR2TACR1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |