Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 11/20 | 0.67 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735866 | 0.94 | SFRP1 (0.66) | SFRP1CNR1CNR2GALK1EPHX2 | |
| SCHEMBL4734796 | 0.94 | SFRP1 (0.66) | SFRP1CNR1CNR2GALK1EPHX2 | |
| SCHEMBL4737386 | 0.94 | SFRP1 (0.72) | SFRP1GALK1EPHX2MAPTIL1RN | |
| SCHEMBL4782887 | 0.94 | SFRP1 (0.72) | SFRP1GALK1EPHX2MAPTIL1RN | |
| SCHEMBL4731278 | 0.93 | SFRP1 (0.71) | SFRP1CNR1CNR2GALK1EPHX2 | |
| SCHEMBL4783929 | 0.92 | SFRP1 (0.63) | SFRP1CNR1CNR2GALK1EPHX2 | |
| SCHEMBL4784004 | 0.91 | SFRP1 (0.66) | SFRP1GALK1EPHX2MAPTIL1RN | |
| SCHEMBL4731282 | 0.90 | SFRP1 (0.67) | SFRP1GALK1EPHX2MAPTIL1RN | |
| SCHEMBL4734355 | 0.89 | SFRP1 (0.75) | SFRP1GALK1EPHX2MAPTIL1RN | |
| SCHEMBL4734031 | 0.89 | SFRP1 (0.64) | SFRP1GALK1EPHX2MAPTIL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |