Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159192 | 0.74 | CRBN (0.33) | DDB1CRBN | |
| SCHEMBL31481321 | 0.73 | OTUD7B (0.45) | DDB1CRBN | |
| SCHEMBL19586502 | 0.71 | CRBN (0.52) | DDB1CRBN | |
| SCHEMBL17112824 | 0.71 | DDB1 (0.30) | DDB1CRBN | |
| SCHEMBL18053975 | 0.70 | USP30 (0.43) | DDB1CRBNSMN1; SMN2 | |
| SCHEMBL31580822 | 0.70 | OTUD7B (0.36) | DDB1CRBN | |
| SCHEMBL30557323 | 0.69 | — | — | |
| SCHEMBL1847022 | 0.68 | CRBN (0.34) | DDB1CRBN | |
| SCHEMBL23859695 | 0.68 | MGLL (0.34) | ALDH1A1 | |
| SCHEMBL19815033 | 0.67 | CRBN (0.31) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060568-A2 | AMIDE-SUBSTITUTED ARYL PIPERIDINES | NEUROGEN CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |