Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 9/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782740 | 0.89 | CNR2 (0.65) | CNR2MAPK1CNR1TDP1 | |
| SCHEMBL4732415 | 0.85 | CNR2 (0.69) | CNR2MAPK1CNR1 | |
| SCHEMBL4782358 | 0.83 | CNR2 (0.52) | CNR2CNR1ALDH1A1 | |
| SCHEMBL4733826 | 0.80 | CNR2 (0.49) | CNR2CNR1ALDH1A1 | |
| SCHEMBL4729137 | 0.79 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4734532 | 0.77 | NPC1 (0.55) | CNR2MAPK1CNR1ALDH1A1 | |
| SCHEMBL4732935 | 0.72 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL14206953 | 0.71 | TDP1 (0.56) | CNR2MAPK1CNR1TDP1ALDH1A1 | |
| SCHEMBL4729959 | 0.71 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL4735443 | 0.69 | CNR2 (0.60) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |