Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.48 |
| ▸ | ABL1 | P00519 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729137 | 0.81 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL14207395 | 0.78 | CNR2 (0.60) | CNR2CNR1ABL1RAB9A | |
| SCHEMBL4729966 | 0.77 | CNR2 (0.41) | CNR2CNR1RAB9A | |
| SCHEMBL14206664 | 0.76 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL4733275 | 0.74 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL4731778 | 0.73 | GAA (0.46) | CNR2CNR1ABL1RAB9A | |
| SCHEMBL4734988 | 0.73 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL4733445 | 0.72 | RAB9A (0.40) | CNR2CNR1ABL1RAB9A | |
| SCHEMBL4731997 | 0.71 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL4732935 | 0.71 | CNR2 (0.77) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |