Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.49 |
| ▸ | CNR1 | P21554 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730721 | 0.86 | CNR2 (0.67) | CNR2CNR1MEN1POLBRECQL | |
| SCHEMBL4782358 | 0.82 | CNR2 (0.52) | CNR2CNR1ALDH1A1 | |
| SCHEMBL4731997 | 0.80 | CNR2 (0.52) | CNR2CNR1ALDH1A1 | |
| SCHEMBL14206432 | 0.73 | ACHE (0.42) | MEN1POLBKMT2AGAAALDH1A1 | |
| SCHEMBL14207385 | 0.70 | CNR2 (0.38) | CNR2CNR1ALDH1A1NPC1RAB9A | |
| SCHEMBL4782740 | 0.68 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL4733274 | 0.67 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL4732146 | 0.67 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL4735445 | 0.66 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL4729561 | 0.65 | CNR2 (0.62) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |