Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 12/20 | 0.59 |
| ▸ | WNT3 | P56703 | 4/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737396 | 0.86 | SFRP1 (0.53) | SFRP1WNT3CCR8SCN9A | |
| SCHEMBL4731736 | 0.85 | SFRP1 (0.54) | SFRP1WNT3CNR1CNR2 | |
| SCHEMBL4733769 | 0.83 | SFRP1 (0.52) | SFRP1WNT3 | |
| SCHEMBL4732944 | 0.83 | SFRP1 (0.62) | SFRP1WNT3CCR8CNR1CNR2 | |
| SCHEMBL4736328 | 0.81 | SFRP1 (0.83) | SFRP1WNT3 | |
| SCHEMBL4616410 | 0.81 | SFRP1 (0.68) | SFRP1WNT3CCR8 | |
| SCHEMBL4733987 | 0.80 | SFRP1 (0.58) | SFRP1WNT3CCR8CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL4732691 | 0.80 | SFRP1 (0.67) | SFRP1WNT3CCR8 | |
| SCHEMBL4856222 | 0.79 | SFRP1 (0.61) | SFRP1WNT3CCR8 | |
| SCHEMBL4735335 | 0.79 | SFRP1 (0.57) | SFRP1WNT3CCR8CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |