Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244381 | 0.83 | KMT2A (0.46) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL3664782 | 0.79 | NPSR1 (0.46) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| SCHEMBL3257322 | 0.77 | NPSR1 (0.44) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL7127166 | 0.77 | NPSR1 (0.44) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| SCHEMBL27457020 | 0.76 | TRPM8 (0.46) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| SCHEMBL6871207 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KMT2AGLAPOLBTSHR | |
| SCHEMBL733882 | 0.72 | ALDH1A1 (0.35) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| Phenol SCHEMBL29260292 | 0.71 | TDP1 (0.42) | NPSR1TRPM8ALDH1A1KMT2ARAB9A | |
| SCHEMBL4236726 | 0.69 | HTT (0.39) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| SCHEMBL3245513 | 0.69 | ALDH1A1 (0.41) | NPSR1ALDH1A1KMT2ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |