Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 16/20 | 0.53 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800869 | 0.96 | FASN (0.49) | FASNPROKR1SLC6A4HRH3EGLN1 | |
| SCHEMBL4800877 | 0.95 | FASN (0.49) | FASNPROKR1SLC6A4HRH3EGLN1 | |
| SCHEMBL4733290 | 0.90 | FASN (0.53) | FASNPROKR1EGLN1ALDH1A1KMT2A | |
| SCHEMBL4736874 | 0.89 | FASN (0.53) | FASNPROKR1EGLN1ALDH1A1KMT2A | |
| SCHEMBL4734375 | 0.88 | FASN (0.66) | FASNPROKR1EGLN1 | |
| SCHEMBL4734368 | 0.85 | FASN (0.53) | FASNPROKR1EGLN1 | |
| SCHEMBL4734716 | 0.83 | FASN (0.49) | FASNPROKR1EGLN1 | |
| SCHEMBL4735905 | 0.83 | FASN (0.63) | FASNPROKR1EGLN1 | |
| SCHEMBL4733280 | 0.82 | FASN (0.69) | FASNPROKR1EGLN1ALDH1A1 | |
| SCHEMBL4735662 | 0.82 | FASN (0.59) | FASNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |