Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 13/20 | 0.66 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.48 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.48 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732391 | 0.91 | FASN (0.67) | FASNLMNA | |
| SCHEMBL4737867 | 0.90 | FASN (0.68) | FASNLMNA | |
| SCHEMBL4735905 | 0.89 | FASN (0.63) | FASNPROKR1EGLN1 | |
| SCHEMBL4734368 | 0.89 | FASN (0.53) | FASNPROKR1EGLN1 | |
| SCHEMBL4733290 | 0.89 | FASN (0.53) | FASNPROKR1CSF1REGLN1 | |
| SCHEMBL4733280 | 0.88 | FASN (0.69) | FASNPROKR1EGLN1 | |
| SCHEMBL4732413 | 0.88 | FASN (0.69) | FASNLMNA | |
| SCHEMBL4732202 | 0.88 | FASN (0.53) | FASNPROKR1EGLN1 | |
| SCHEMBL4736874 | 0.88 | FASN (0.53) | FASNPROKR1EGLN1 | |
| SCHEMBL4736480 | 0.87 | FASN (0.68) | FASNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | claimed |
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |