Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 16/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735905 | 0.90 | FASN (0.63) | FASNEGLN1PROKR1 | |
| SCHEMBL4737584 | 0.90 | FASN (0.74) | FASN | |
| SCHEMBL4736239 | 0.90 | FASN (0.74) | FASN | |
| SCHEMBL4737156 | 0.88 | FASN (0.72) | FASN | |
| SCHEMBL4734375 | 0.88 | FASN (0.66) | FASNEGLN1PROKR1 | |
| SCHEMBL4733303 | 0.88 | FASN (0.60) | FASNEGLN1PROKR1 | |
| SCHEMBL16802696 | 0.88 | FASN (0.69) | FASN | |
| SCHEMBL4731407 | 0.88 | FASN (0.71) | FASN | |
| SCHEMBL4784807 | 0.87 | FASN (0.70) | FASN | |
| SCHEMBL4731958 | 0.87 | FASN (0.72) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |