Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067234 | 0.66 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EMEN1MAPK1 | |
| SCHEMBL18711692 | 0.63 | SPR (0.48) | ALDH1A1ALPLHIF1ASPRMEN1 | |
| SCHEMBL10280073 | 0.62 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL3109830 | 0.62 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL31233784 | 0.62 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EPARP1SLC6A5 | |
| SCHEMBL1621750 | 0.62 | ALDH1A1 (0.91) | ALDH1A1MAPTHSD17B10KDM4EKMT2A | |
| SCHEMBL23976051 | 0.61 | ALDH1A1 (0.39) | ALDH1A1MAPTPARP1TNKS2 | |
| SCHEMBL1834695 | 0.61 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EGLAGAA | |
| SCHEMBL15847335 | 0.61 | ALDH1A1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL2725109 | 0.61 | ALDH1A1 (0.35) | ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |