Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 12/20 | 0.67 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735662 | 0.92 | FASN (0.59) | FASNNAMPTLMNAPRSS12MEN1 | |
| SCHEMBL4734375 | 0.91 | FASN (0.66) | FASNLMNA | |
| SCHEMBL4737867 | 0.91 | FASN (0.68) | FASNLMNA | |
| SCHEMBL4732413 | 0.89 | FASN (0.69) | FASNLMNA | |
| SCHEMBL4785104 | 0.88 | FASN (0.65) | FASNLMNA | |
| SCHEMBL4736480 | 0.88 | FASN (0.68) | FASNLMNAPRSS12POLBMEN1 | |
| SCHEMBL4732219 | 0.87 | FASN (0.73) | FASN | |
| SCHEMBL16799740 | 0.85 | FASN (0.53) | FASNNAMPTPRSS12 | |
| SCHEMBL19724247 | 0.84 | FASN (0.49) | FASNLMNAPRSS12MEN1KMT2A | |
| SCHEMBL4202962 | 0.82 | FASN (0.61) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | claimed |
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |