Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 16/20 | 0.65 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737867 | 0.89 | FASN (0.68) | FASNLMNA | |
| SCHEMBL4732391 | 0.88 | FASN (0.67) | FASNLMNA | |
| SCHEMBL4732413 | 0.87 | FASN (0.69) | FASNLMNA | |
| SCHEMBL4734375 | 0.87 | FASN (0.66) | FASNLMNA | |
| SCHEMBL4736480 | 0.86 | FASN (0.68) | FASNLMNA | |
| SCHEMBL4783802 | 0.86 | FASN (0.66) | FASN | |
| SCHEMBL4732219 | 0.86 | FASN (0.73) | FASN | |
| SCHEMBL4732716 | 0.81 | FASN (0.70) | FASN | |
| SCHEMBL4735662 | 0.81 | FASN (0.59) | FASNLMNA | |
| SCHEMBL4182755 | 0.81 | FASN (0.57) | FASNMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | claimed |