SCHEMBL4732404

SCHEMBL4732404

COc1ccc(C2CCN(C(=O)c3ccc(C)c(NC(=O)c4ccc(NC(C)=O)nc4)c3)CC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 19/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732251 0.90 FASN (0.78) FASN
SCHEMBL4737151 0.90 FASN (0.62) FASN
SCHEMBL4731968 0.89 FASN (0.60) FASN
SCHEMBL4733983 0.89 FASN (0.60) FASN
SCHEMBL4734752 0.89 FASN (0.60) FASN
SCHEMBL4784807 0.88 FASN (0.70) FASN
SCHEMBL16799594 0.88 FASN (0.75) FASN
SCHEMBL4733412 0.87 FASN (0.60) FASN
SCHEMBL4736245 0.87 FASN (0.79) FASN
SCHEMBL4735650 0.86 FASN (0.61) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO claimed
WO-2008059214-A1 BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS ASTRAZENECA AB (SE) 2008-05-22 WO disclosed