Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 18/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732404 | 0.90 | FASN (0.63) | FASN | |
| SCHEMBL4736245 | 0.89 | FASN (0.79) | FASN | |
| SCHEMBL4733412 | 0.89 | FASN (0.60) | FASN | |
| SCHEMBL4737156 | 0.87 | FASN (0.72) | FASNTP53MAPT | |
| SCHEMBL4734689 | 0.86 | FASN (0.61) | FASN | |
| SCHEMBL4733279 | 0.85 | FASN (0.62) | FASNTP53MAPT | |
| SCHEMBL4731256 | 0.85 | FASN (0.56) | FASNTP53MAPT | |
| SCHEMBL4731416 | 0.85 | FASN (0.61) | FASNTP53MAPT | |
| SCHEMBL19396043 | 0.85 | FASN (0.85) | FASN | |
| SCHEMBL16799457 | 0.85 | FASN (0.75) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | claimed |
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |