Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737151 | 0.89 | FASN (0.62) | FASN | |
| SCHEMBL4735658 | 0.88 | FASN (0.69) | FASN | |
| SCHEMBL4732404 | 0.87 | FASN (0.63) | FASN | |
| SCHEMBL4736245 | 0.87 | FASN (0.79) | FASN | |
| SCHEMBL4734574 | 0.87 | FASN (0.58) | FASN | |
| SCHEMBL4782991 | 0.84 | FASN (0.68) | FASN | |
| SCHEMBL14209160 | 0.81 | FASN (0.64) | FASN | |
| SCHEMBL4735774 | 0.81 | FASN (0.64) | FASN | |
| SCHEMBL14209877 | 0.80 | FASN (0.58) | FASN | |
| SCHEMBL4784111 | 0.80 | FASN (0.72) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | claimed |
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |