Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562227 | 0.97 | — | — | |
| Iodide SCHEMBL5047411 | 0.95 | — | — | |
| Bromide SCHEMBL4727960 | 0.93 | NOS1 (0.82) | — | |
| Bromide SCHEMBL4785272 | 0.91 | NOS1 (0.78) | — | |
| Cyanide SCHEMBL9498925 | 0.91 | NOS1 (0.86) | — | |
| Bromide SCHEMBL4732328 | 0.91 | NOS1 (0.78) | — | |
| Bromide SCHEMBL9841020 | 0.91 | NOS1 (0.78) | — | |
| SCHEMBL6216529 | 0.90 | — | — | |
| SCHEMBL27409769 | 0.89 | NOS1 (0.83) | — | |
| SCHEMBL11590702 | 0.88 | NOS1 (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044033-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-04-17 | — | — | WO | disclosed |