Cyanide

Cyanide

SCHEMBL9498925

C#N.CCCCSC(=N)N

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 6/20 0.86
NOS3 P29474 4/20 0.86
NOS2 P35228 4/20 0.86
CYP1A2 P05177 5/20 0.54
CYP2C19 P33261 3/20 0.54
HRH4 Q9H3N8 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
ALDH1A1 P00352 2/20 0.52
HRH2 P25021 1/20 0.52
HSD17B10 Q99714 1/20 0.50
TSHR P16473 2/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 2/20 0.46
BLM P54132 1/20 0.46
LMNA P02545 2/20 0.44
CYP3A4 P08684 1/20 0.44
APEX1 P27695 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HRH3 Q9Y5N1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562227 0.93
Bromide SCHEMBL4732426 0.91
Iodide SCHEMBL5047411 0.91
SCHEMBL27409769 0.89 NOS1 (0.83) NOS1NOS3NOS2CYP1A2CYP2C19
SCHEMBL6216529 0.86
SCHEMBL9322246 0.84 NOS1 (0.82) NOS1NOS3NOS2CYP1A2CYP2C19
SCHEMBL14085945 0.84 NOS1 (0.82) NOS1NOS3NOS2CYP1A2CYP2C19
SCHEMBL11590702 0.84 NOS1 (0.82) NOS1NOS3NOS2CYP1A2CYP2C19
Bromide SCHEMBL4727960 0.84 NOS1 (0.82) NOS1NOS3NOS2CYP1A2CYP2C19
SCHEMBL31240346 0.84 NOS1 (0.82) NOS1NOS3NOS2CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558799-A2 Catalyst and process for the production of 3-cyano-3,5,5-trialkylcyclohexanone ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-09-08 EP disclosed
US-5183915-A Reacting with hydrocyanide in presence of quaternary ammonium or phosphonium cyanide in absence of water ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-02-02 US disclosed