Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731976 | 1.00 | CA2 (0.49) | CA2TP53GPR84CA1FFAR1 | |
| SCHEMBL4732394 | 1.00 | CA2 (0.49) | CA2TP53GPR84CA1FFAR1 | |
| SCHEMBL14166660 | 0.93 | CA2 (0.49) | CA2TP53GPR84CA1EPHX1 | |
| SCHEMBL14566014 | 0.84 | GPR84 (0.50) | CA2GPR84FFAR1FAAHMAPT | |
| SCHEMBL11310381 | 0.81 | TP53 (0.50) | CA2TP53GPR84CA1FFAR1 | |
| SCHEMBL6240268 | 0.81 | TP53 (0.50) | CA2TP53GPR84CA1FFAR1 | |
| SCHEMBL4814530 | 0.81 | TP53 (0.50) | CA2TP53GPR84CA1FFAR1 | |
| SCHEMBL29211666 | 0.81 | TP53 (0.46) | CA2TP53GPR84CA1FFAR1 | |
| SCHEMBL2807679 | 0.81 | CA2 (0.50) | CA2TP53CA1EPHX1 | |
| SCHEMBL27321007 | 0.80 | TP53 (0.39) | CA2TP53GPR84CA1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044033-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-04-17 | — | — | WO | disclosed |