⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426122 | 0.80 | NPC1 (0.33) | — | |
| SCHEMBL22284141 | 0.70 | NPC1 (0.30) | — | |
| SCHEMBL8763585 | 0.70 | — | — | |
| SCHEMBL18601372 | 0.69 | — | — | |
| SCHEMBL1659876 | 0.69 | HTT (0.37) | — | |
| SCHEMBL18601366 | 0.69 | — | — | |
| SCHEMBL11659083 | 0.68 | THRB (0.36) | — | |
| SCHEMBL15234704 | 0.66 | HTT (0.42) | — | |
| Hexamethylbenzene SCHEMBL27477496 | 0.64 | TSHR (0.58) | — | |
| SCHEMBL8426258 | 0.64 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108638-A1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT AND SKIN TIGHTENING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-04-04 | — | — | US | disclosed |
| US-20220047499-A1 | Topical Lipolysis Composition and Methods | LIPODISSOLVE THERAPEUTICS INC (CA) | 2022-02-17 | — | — | US | disclosed |
| EP-3692995-A1 | DEOXYCHOLATE FOR REDUCTION OF FAT | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (US) | 2020-08-12 | — | — | EP | disclosed |
| CN-106661565-B | Lactase solution and milk using the same | 合同酒精株式会社 | 2020-04-21 | — | — | CN | disclosed |
| EP-2380576-B1 | Use of sodium deoxycholate for the non-surgical removal of fat | LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-1845938-B1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT AND SKIN TIGHTENING | LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) | 2019-04-03 | — | — | EP | disclosed |
| US-20190015427-A1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT AND SKIN TIGHTENING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-01-17 | — | — | US | disclosed |
| US-10058561-B2 | Methods and related compositions for reduction of fat and skin tightening | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-08-28 | — | — | US | disclosed |
| US-9750821-B2 | Gas-filled microvesicle assembly for contrast imaging | BRACCO SUISSE S.A. (CH) | 2017-09-05 | — | — | US | disclosed |
| US-20170245513-A1 | LACTASE SOLUTION AND MILK USING SAME | GODO SHUSEI CO., LTD. (JP) | 2017-08-31 | — | — | US | disclosed |
| EP-1701745-A1 | GAS-FILLED MICROVESICLE ASSEMBLY FOR CONTRAST IMAGING | BRACCO RESEARCH S.A. (CH) | 2006-09-20 | — | — | EP | disclosed |
| EP-1696965-A1 | ASSEMBLY OF GAS-FILLED MICROVESICLE WITH ACTIVE COMPONENT FOR CONTRAST IMAGING | BRACCO RESEARCH S.A. (CH) | 2006-09-06 | — | — | EP | disclosed |
| WO-2006086038-A1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT AND SKIN TIGHTENING | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20060127468-A1 | Methods and related compositions for reduction of fat and skin tightening | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER | 2006-06-15 | — | — | US | disclosed |
| WO-2005117832-A1 | LIPOSOMAL ASSEMBLY FOR THERAPEUTIC AND/OR DIAGNOSTIC USE | BRACCO RESEARCH SA (CH) | 2005-12-15 | — | — | WO | disclosed |
| US-20050267080-A1 | Methods and related compositions for reduction of fat | AESTHERX, INC. | 2005-12-01 | — | — | US | disclosed |
| WO-2005112942-A1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005063306-A1 | ASSEMBLY OF GAS-FILLED MICROVESICLE WITH ACTIVE COMPONENT FOR CONTRAST IMAGING | BRACCO RESEARCH SA (CH) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005063305-A1 | GAS-FILLED MICROVESICLE ASSEMBLY FOR CONTRAST IMAGING | BRACCO RESEARCH SA (CH) | 2005-07-14 | — | — | WO | disclosed |
| US-4425306-A | SOLVENT EXTRACTION, PHENYLPYROPHOSPHATE | STAUFFER CHEMICAL COMPANY (US) | 1984-01-10 | — | — | US | disclosed |