Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426122 | 0.75 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2139146 | 0.71 | NPC1 (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL815026 | 0.68 | NPC1 (0.34) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL7570622 | 0.66 | HPGD (0.33) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL29022222 | 0.65 | HTT (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8763585 | 0.65 | — | — | |
| SCHEMBL8647839 | 0.65 | TYR (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1659876 | 0.64 | HTT (0.37) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL473271 | 0.64 | — | — | |
| SCHEMBL11659083 | 0.64 | THRB (0.36) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939228-A | WATERPROOF SUPPORTS AND IMAGE RECEIVER LAYERS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |