Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270791 | 0.91 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL316956 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPTATMTDP1LMNA | |
| SCHEMBL21065601 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL11270799 | 0.84 | CYP4F2 (0.52) | ALDH1A1MAPTKMT2ASMN1; SMN2NPC1 | |
| Ammonia Solution, Strong SCHEMBL27749588 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPTATMTDP1LMNA | |
| SCHEMBL21065590 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1TDP1ELANE | |
| SCHEMBL22749297 | 0.82 | AKR1C3 (0.55) | ALDH1A1MAPTLMNAPTGS2MEN1 | |
| SCHEMBL4167297 | 0.81 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL2489987 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTNPC1 | |
| SCHEMBL28458575 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTATMTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060844-A1 | POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ALBEMARLE CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |