SCHEMBL21065601

SCHEMBL21065601

C=C(C(=O)OCC)c1cccc(-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
MAPT P10636 1/20 0.56
DHODH Q02127 2/20 0.52
KMO O15229 1/20 0.49
ERCC5 P28715 1/20 0.45
FEN1 P39748 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11270791 0.87 ALDH1A1 (0.57) ALDH1A1MAPT
SCHEMBL21065617 0.86 MAPT (0.57) ALDH1A1MAPTDHODH
SCHEMBL316956 0.85 ALDH1A1 (0.69) ALDH1A1MAPT
SCHEMBL4732769 0.85 ALDH1A1 (0.56) ALDH1A1MAPT
SCHEMBL12745989 0.84 ALDH1A1 (0.55) ALDH1A1MAPTDHODHKMOERCC5
Ammonia Solution, Strong SCHEMBL27749588 0.84 ALDH1A1 (0.67) ALDH1A1MAPT
SCHEMBL21065590 0.83 ALDH1A1 (0.53) ALDH1A1MAPTHDAC8
SCHEMBL22749297 0.82 AKR1C3 (0.55) ALDH1A1MAPTERCC5FEN1HDAC8
SCHEMBL2631517 0.82 ALDH1A1 (0.53) ALDH1A1MAPTDHODHKMOERCC5
SCHEMBL2489987 0.81 ALDH1A1 (0.51) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN claimed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 CN claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN disclosed
CN-116888193-A Polysiloxane vinyl cross-linking agent with high refractive index 爱尔康公司 2023-10-13 CN disclosed
CN-115698776-A Insert material with high oxygen permeability coefficient and high refractive index 爱尔康公司 2023-02-03 CN disclosed
CN-111712523-B Ophthalmic product composition 爱尔兰眼力健公司 2023-01-03 CN disclosed
CN-115298574-A Embedded silicone hydrogel contact lenses 爱尔康公司 2022-11-04 CN disclosed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN disclosed
EP-3728339-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2020-10-28 EP disclosed
CN-111712523-A Ophthalmic product composition 默克专利股份有限公司 2020-09-25 CN disclosed
CN-106999629-B Low water content acrylate-acrylamide copolymers for ophthalmic devices 诺华股份有限公司 2020-02-21 CN disclosed
EP-3502147-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2019-06-26 EP disclosed
CN-102007111-A Stabilization and surface modification of organic materials BASF SE 2011-04-06 CN disclosed