Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 12/20 | 0.80 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.53 |
| ▸ | WNT3 | P56703 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617114 | 0.89 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL4731882 | 0.89 | SFRP1 (0.70) | SFRP1SLC22A12 | |
| SCHEMBL4733249 | 0.83 | SFRP1 (0.68) | SFRP1 | |
| SCHEMBL4733325 | 0.82 | SFRP1 (0.81) | SFRP1 | |
| SCHEMBL4732854 | 0.81 | SFRP1 (0.63) | SFRP1 | |
| SCHEMBL4735547 | 0.81 | SFRP1 (0.60) | SFRP1SLC22A12WNT3 | |
| SCHEMBL4734031 | 0.78 | SFRP1 (0.64) | SFRP1 | |
| SCHEMBL4733180 | 0.77 | SFRP1 (0.82) | SFRP1 | |
| SCHEMBL4669646 | 0.76 | SFRP1 (0.78) | SFRP1WNT3 | |
| SCHEMBL4619009 | 0.76 | SFRP1 (1.00) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |