Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238932 | 0.83 | POLB (0.68) | SMN1; SMN2HTTMEN1KMT2ANPSR1 | |
| SCHEMBL4737601 | 0.83 | FASN (0.59) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL7231708 | 0.82 | FAAH (0.62) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL4736936 | 0.82 | KDM4E (0.72) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL4731259 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL10242022 | 0.81 | MEN1 (0.71) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL7238877 | 0.81 | CYP2C9 (0.67) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL10719972 | 0.79 | HTT (0.78) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL4732268 | 0.79 | FASN (0.59) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL29941294 | 0.79 | HTT (0.69) | SMN1; SMN2HTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |