Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732887 | 1.00 | ACHE (0.52) | ACHEBACE1CMKLR1FPR2NFKB1 | |
| SCHEMBL1376304 | 0.92 | PPARG (0.51) | ACHEBACE1NFKB1PPARGGPR132 | |
| SCHEMBL1376307 | 0.92 | PPARG (0.51) | ACHEBACE1NFKB1PPARGGPR132 | |
| Adipic Acid SCHEMBL6760249 | 0.85 | FFAR1 (0.55) | ACHEBACE1PPARGGPR132 | |
| Glutarate SCHEMBL11026421 | 0.83 | ACHE (0.53) | ACHEBACE1FPR2NFKB1NFKB2 | |
| SCHEMBL2763308 | 0.83 | ACHE (0.52) | ACHEBACE1CMKLR1MAPTPPARG | |
| SCHEMBL8828842 | 0.81 | ACHE (0.76) | ACHEBACE1FPR2NFKB1NFKB2 | |
| SCHEMBL8090945 | 0.81 | ACHE (0.76) | ACHEBACE1FPR2NFKB1NFKB2 | |
| SCHEMBL4745520 | 0.79 | ACHE (0.49) | ACHEBACE1MAPTPPARGGPR132 | |
| SCHEMBL4760946 | 0.79 | ACHE (0.53) | ACHEBACE1FPR2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187511-A1 | Comprises phostphatidylserine and oil-based carrier; for topical or intratumoral administration; aminophospholipid translocase inhibitors; transnitrosylating agents; chemokines; cytokines; Toll-like receptor ligands; dendritic cell differentiation factors; neoplasm | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH | 2008-08-07 | — | — | US | disclosed |
| WO-2008052126-A2 | OINTMENT COMPRISING PHOSPHATIDYLSERINE AS ACTIVE AGENT FOR CANCER TREATMENT | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-05-02 | — | — | WO | disclosed |