Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561406 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL15286996 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL27963352 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL15287182 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL4759937 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL649787 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL4745520 | 0.92 | ACHE (0.49) | ACHEBACE1CAMK2AGABRPGABRD | |
| SCHEMBL5410871 | 0.86 | ACHE (0.46) | ACHEBACE1GABRPGABRDGABRA1 | |
| Adipic Acid SCHEMBL6760249 | 0.85 | FFAR1 (0.55) | ACHEBACE1CAMK2AGPR84FFAR1 | |
| SCHEMBL4732889 | 0.83 | ACHE (0.52) | ACHEBACE1MAPTCMKLR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131814-B2 | Radiation-curable water-dispersible polyurethane (meth)acrylates | BASF SE (DE) | 2018-11-20 | — | — | US | claimed |
| EP-1274401-A4 | STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING 7-SUBSTITUTED-3,5-DIHYDROXYHEPTANOIC ACIDS OR 7-SUBSTITUTED-3,5-DIHYDROXYHEPTENOIC ACIDS | TEVA PHARMA (IL) | 2009-07-22 | — | — | EP | claimed |
| EP-1274401-A1 | STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING 7-SUBSTITUTED-3,5-DIHYDROXYHEPTANOIC ACIDS OR 7-SUBSTITUTED-3,5-DIHYDROXYHEPTENOIC ACIDS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-01-15 | — | — | EP | claimed |
| EP-1268589-A1 | ACRYLIC RUBBER LATEX HAVING BIMODAL PARTICLE DISTRIBUTION | LG Chem Ltd. (KR) | 2003-01-02 | — | — | EP | claimed |
| WO-2002055572-A1 | ACRYLIC RUBBER LATEX HAVING BIMODAL PARTICLE DISTRIBUTION | LG CHEM, LTD. (KR) | 2002-07-18 | — | — | WO | claimed |
| WO-2001076566-A1 | STABLE PHARMACEUTICAL COMPOSITIONS CONTAINING 7-SUBSTITUTED-3,5-DIHYDROXYHEPTANOIC ACIDS OR 7-SUBSTITUTED-3,5-DIHYDROXYHEPTENOIC ACIDS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2001-10-18 | — | — | WO | claimed |
| US-20130237579-A1 | STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE HMG-COA REDUCTAS INHIBITIORS | STANLEY TIMOTHY (GB) | 2013-09-12 | — | — | US | disclosed |
| EP-2178515-A2 | STABLE COMPOSITIONS | Generics Ýuk¨Limited (GB) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009010787-A2 | STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE HMG-COA REDUCTASE INHIBITORS | GENERICS [UK] LIMITED (GB) | 2009-01-22 | — | — | WO | disclosed |
| EP-1644198-A1 | INK JET RECORDING MEDIUM | Ciba SC Holding AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005155-A1 | INK JET RECORDING MEDIUM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-01-20 | — | — | WO | disclosed |
| EP-1268589-A1 | ACRYLIC RUBBER LATEX HAVING BIMODAL PARTICLE DISTRIBUTION | LG Chem Ltd. (KR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002055572-A1 | ACRYLIC RUBBER LATEX HAVING BIMODAL PARTICLE DISTRIBUTION | LG CHEM, LTD. (KR) | 2002-07-18 | — | — | WO | disclosed |
| US-5387693-A | Intermediates for inhibitors of cholesterol biosynthesis | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-02-07 | — | — | US | disclosed |
| US-5315012-A | Prevention of hypercholesterolemia, hyperlipoproteinemia and atherosclerosis | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| US-5250561-A | Anticholesterool agents; prevention of hyperlipoproteinemia and atherosclerosis | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0529854-A2 | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-COA reductase inhibitors | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5134155-A | Anticholesterol | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |
| US-4792614-A | ANTIHYPER CHOLESTEROL AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |