Pyridine

Pyridine

SCHEMBL4733223

O=COCl.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL455048 0.82 ALDH1A1 (0.30)
Pyridine SCHEMBL15207104 0.79
Pyridine SCHEMBL873515 0.78
Pyridine SCHEMBL27958636 0.78 TSHR (0.50) TSHRNAPRTTDP1
Pyridine SCHEMBL28412077 0.78 TDP1 (0.50) TSHRNAPRTTDP1
Pyridine SCHEMBL27835773 0.78 TSHR (0.50) TSHRNAPRTTDP1
Pyridine SCHEMBL27346185 0.77 TSHR (0.56) TSHRNAPRTTDP1
Pyridine SCHEMBL6265602 0.76 TSHR (0.47) TSHRNAPRTTDP1
Pyridine SCHEMBL10542959 0.76 TSHR (0.64) TSHRNAPRTTDP1
Pyridine SCHEMBL27955340 0.76 TSHR (0.64) TSHRNAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978750-A2 \"SYNTHESIS OF DABIGATRAN\ USV Limited (IN) 2016-02-03 EP disclosed
WO-2014167577-A2 \"SYNTHESIS OF DABIGATRAN\ USV LIMITED (IN) 2014-10-16 WO disclosed
WO-2008072078-A1 AN IMPROVED PROCESS FOR PREPARING ROSUVASTATIN CACLIUM AUROBINDO PHARMA LIMITED (IN) 2008-06-19 WO disclosed