Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441079 | 0.85 | SMN1; SMN2 (0.42) | NPSR1GFERNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3847249 | 0.83 | HRH4 (0.42) | NPC1RAB9ASMN1; SMN2HRH3EGFR | |
| SCHEMBL5044641 | 0.78 | NPC1 (0.46) | NPSR1GFERNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29991257 | 0.77 | KDM4E (0.59) | NPC1RAB9ASMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL20595527 | 0.77 | KDM4E (0.59) | NPC1RAB9ASMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL4758202 | 0.76 | POLB (0.43) | NPC1RAB9ASMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL4439862 | 0.76 | POLB (0.43) | NPC1RAB9ASMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL16487837 | 0.76 | CYP1A2 (0.51) | NPC1RAB9ASMN1; SMN2EGFRALDH1A1 | |
| SCHEMBL3839965 | 0.73 | CBFB (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5047854 | 0.73 | MAPK10 (0.42) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071981-A1 | PIPERIDINES FOR THE TREATMENT OF BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | WO | disclosed |