SCHEMBL4733378

SCHEMBL4733378

CCCCC(C)OC(=O)c1cc(O)c(O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.58
AKR1C4 P17516 1/20 0.55
AKR1C3 P42330 1/20 0.55
AKR1C2 P52895 1/20 0.55
AKR1C1 Q04828 1/20 0.55
SERPINE1 P05121 5/20 0.51
PRKCA P17252 2/20 0.50
PRKCD Q05655 2/20 0.50
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
NFKB1 P19838 1/20 0.47
XDH P47989 1/20 0.47
GFER P55789 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
FUT7 Q11130 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4735692 0.95 ESR1 (0.57) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL4735045 0.94 ESR1 (0.60) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL4735640 0.94 ESR1 (0.60) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL4734869 0.94 ESR1 (0.60) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL4733780 0.94 ESR1 (0.60) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL25142271 0.90 SERPINE1 (0.54) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL20082325 0.86 ESR1 (0.59) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL4733699 0.84 PRKCA (0.69) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL39233 0.83 SERPINE1 (0.57) ESR1AKR1C4AKR1C3AKR1C2AKR1C1
SCHEMBL21275726 0.83 ESR1 (0.61) ESR1AKR1C4AKR1C3AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008065527-A2 GALLIC ACID ESTERS OF FRAGRANT ALCOHOLS GHISALBERTI CARLO (BR) 2008-06-05 WO disclosed