SCHEMBL39233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25142271	0.86	SERPINE1 (0.54)	SERPINE1KDM4ELMNAPOLBGAA
	SCHEMBL7930132	0.85	SERPINE1 (0.50)	SERPINE1KDM4ELMNAPOLBGAA
	SCHEMBL39052	0.84	CA12 (0.67)	SERPINE1L3MBTL1PRKCAPRKCDCA12
	SCHEMBL23066477	0.84	CA12 (0.61)	SERPINE1LMNAL3MBTL1PRKCAPRKCD
	SCHEMBL4733378	0.83	ESR1 (0.58)	SERPINE1KDM4ELMNAPOLBGAA
	SCHEMBL7930131	0.83	SERPINE1 (0.51)	SERPINE1KDM4ELMNAPOLBGAA
	SCHEMBL4137305	0.83	SERPINE1 (0.73)	SERPINE1KDM4ELMNAPOLBGAA
	SCHEMBL4733522	0.83	PRKCA (0.68)	SERPINE1KDM4ELMNAPOLBGAA
	SCHEMBL38649	0.83	CA12 (0.70)	KDM4EPOLBGAAXDHL3MBTL1
	SCHEMBL14346381	0.83	ESR1 (0.54)	SERPINE1GAAL3MBTL1ESR1PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.