Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 18/20 | 0.71 |
| ▸ | WNT3 | P56703 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735625 | 0.91 | SFRP1 (0.66) | SFRP1WNT3EPHX2 | |
| SCHEMBL4735101 | 0.90 | SFRP1 (0.66) | SFRP1WNT3EPHX2 | |
| SCHEMBL4737870 | 0.90 | SFRP1 (0.65) | SFRP1WNT3EPHX2 | |
| SCHEMBL4888536 | 0.89 | SFRP1 (0.64) | SFRP1WNT3EPHX2 | |
| SCHEMBL4731611 | 0.89 | SFRP1 (0.69) | SFRP1WNT3EPHX2 | |
| SCHEMBL4736407 | 0.89 | SFRP1 (0.63) | SFRP1WNT3EPHX2 | |
| SCHEMBL4784205 | 0.89 | SFRP1 (0.63) | SFRP1WNT3EPHX2 | |
| SCHEMBL4732405 | 0.89 | SFRP1 (0.77) | SFRP1WNT3EPHX2 | |
| SCHEMBL4732834 | 0.88 | SFRP1 (0.59) | SFRP1WNT3 | |
| SCHEMBL4732579 | 0.88 | SFRP1 (0.88) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |