Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783553 | 0.85 | CNR2 (0.53) | CNR2CNR1TSHRKDM4EALDH1A1 | |
| SCHEMBL14206664 | 0.81 | CNR2 (0.58) | CNR2CNR1TSHRALDH1A1MEN1 | |
| SCHEMBL4729959 | 0.77 | CNR2 (0.51) | CNR2CNR1RAB9A | |
| SCHEMBL4730642 | 0.76 | ALDH1A1 (0.47) | CNR2TSHRALDH1A1RAB9AKMT2A | |
| SCHEMBL4733445 | 0.74 | RAB9A (0.40) | CNR2CNR1KDM4EALDH1A1MEN1 | |
| SCHEMBL4733798 | 0.74 | CNR2 (0.45) | CNR2CNR1TSHRKDM4EALDH1A1 | |
| SCHEMBL4733593 | 0.74 | CNR2 (0.52) | CNR2CNR1MEN1RAB9AKMT2A | |
| SCHEMBL4734267 | 0.73 | CNR2 (0.50) | CNR2CNR1TSHRMEN1RAB9A | |
| SCHEMBL4729137 | 0.71 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4732445 | 0.67 | CNR2 (0.53) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |