Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butanone SCHEMBL27467891 | 0.89 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRCES2HPGD | |
| SCHEMBL113503 | 0.89 | — | — | |
| SCHEMBL15510719 | 0.89 | — | — | |
| SCHEMBL8506709 | 0.86 | — | — | |
| Isopropyl Alcohol SCHEMBL1641692 | 0.86 | TSHR (0.39) | ALDH1A1ATMTSHR | |
| Water SCHEMBL9170507 | 0.86 | — | — | |
| Methyl Alcohol SCHEMBL14895379 | 0.86 | TSHR (0.39) | ALDH1A1ATMTSHR | |
| Adipic Acid SCHEMBL27174192 | 0.86 | AKR1B1 (0.56) | ALDH1A1TSHRGPR84FFAR1 | |
| Methyl Isobutyl Ketone SCHEMBL16531183 | 0.84 | ALDH1A1 (0.52) | ALDH1A1ATMPLA2G4BTSHRFFAR1 | |
| Alcohol SCHEMBL2853368 | 0.84 | TSHR (0.42) | ALDH1A1ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397402-B1 | LOW BAKE AUTODEPOSITION COATINGS | HENKEL AG & CO KGAA (DE) | 2023-05-24 | — | — | EP | claimed |
| US-11426762-B2 | Low bake autodeposition coatings | HENKEL AG & CO. KGAA (DE) | 2022-08-30 | — | — | US | claimed |
| EP-3397402-A1 | LOW BAKE AUTODEPOSITION COATINGS | Henkel AG & Co. KGaA (DE) | 2018-11-07 | — | — | EP | claimed |
| US-20180304306-A1 | LOW BAKE AUTODEPOSITION COATINGS | HENKEL AG & CO. KGAA (DE) | 2018-10-25 | — | — | US | claimed |
| WO-2017117169-A1 | LOW BAKE AUTODEPOSITION COATINGS | HENKEL AG & CO. KGAA (DE) | 2017-07-06 | — | — | WO | claimed |
| EP-1411886-B1 | NON-AEROSOL SHAVING GEL | GILLETTE CO (US) | 2005-02-23 | — | — | EP | claimed |
| US-20040251451-A1 | Lacquer layer, which reflects infra-red radiation | AIR PRODUCTS AND CHEMICALS, INC. | 2004-12-16 | — | — | US | claimed |
| EP-1458823-A1 | LACQUER LAYER REFLECTING INFRA-RED RADIATION | Nanogate Technologies GmbH (DE) | 2004-09-22 | — | — | EP | claimed |
| EP-1411886-A2 | NON-AEROSOL SHAVING GEL | THE GILLETTE COMPANY (US) | 2004-04-28 | — | — | EP | claimed |
| US-6627185-B2 | Mixture containing alkanolamine soap | THE GILLETTE COMPANY | 2003-09-30 | — | — | US | claimed |
| WO-2003050193-A1 | LACQUER LAYER, WHICH REFLECTS INFRA-RED RADIATION | NANOGATE TECHNOLOGIES GMBH (DE) | 2003-06-19 | — | — | WO | claimed |
| WO-2003009823-A2 | NON-AEROSOL SHAVING GEL | THE GILLETTE COMPANY (US) | 2003-02-06 | — | — | WO | claimed |
| US-20030021760-A1 | None-aerosol Shaving gel | THE GILLETTE COMPANY LLC | 2003-01-30 | — | — | US | claimed |
| US-4386063-A | WITH 2-PHENYL-3-CARBOETHOXYFURAN AND/OR BIS(CYCLOHEXYL)DISULFIDE; GRAPE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1983-05-31 | — | — | US | claimed |
| US-4357316-A | Use of 1-n-butoxy-1-ethanol acetate for augmenting or enhancing the taste of toothpaste | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-11-02 | — | — | US | claimed |
| US-4354953-A | Process for augmenting or enhancing the aroma of detergents using 1-n-butoxy-1-ethanol acetate | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-10-19 | — | — | US | claimed |
| US-4333481-A | 1-n-Butoxy-1-ethanol acetate and uses thereof for augmenting or enhancing the aroma or taste of consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-06-08 | — | — | US | claimed |
| US-4331571-A | 1-N-Butoxy-1-ethanol acetate useful for augmenting or enhancing the aroma of perfume materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-05-25 | — | — | US | claimed |
| US-4330417-A | 1-N-Butoxy-1-ethanol acetate and uses thereof for augmenting or enhancing the aroma or taste of consumable materials | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-05-18 | — | — | US | claimed |
| US-4296138-A | FOR FOOD, CHEWING GUM | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-10-20 | — | — | US | claimed |