Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735007 | 0.92 | POLB (0.63) | LMNAMAPK10POLBNPC1RAB9A | |
| SCHEMBL4735004 | 0.88 | NPC1 (0.54) | LMNAPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4734498 | 0.87 | LMNA (0.78) | LMNAMAPK10POLBNPC1RAB9A | |
| SCHEMBL4737597 | 0.84 | POLB (0.59) | LMNAMAPK10POLBNPC1RAB9A | |
| SCHEMBL4737760 | 0.82 | GRIK1 (0.57) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7033057 | 0.78 | PPARG (0.61) | LMNAMAPK10POLBNPC1RAB9A | |
| SCHEMBL4749629 | 0.78 | NPC1 (0.61) | LMNAMAPK10POLBNPC1RAB9A | |
| SCHEMBL4749274 | 0.77 | SMN1; SMN2 (0.56) | LMNAMAPK10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4738815 | 0.77 | NPC1 (0.48) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4736542 | 0.76 | SMN1; SMN2 (0.58) | LMNAMAPK10POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |